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In humans, sex determination is the process that determines the biological sex of an offspring and, as a result, the sexual characteristics that they will develop. Humans typically develop as either male or female, primarily depending on the combination of sex chromosomes that they inherit from their parents.
The human sex chromosomes, called X and Y, are structures in human cells made up of tightly bound deoxyribonucleic acid, or DNA, and proteins. Those are molecules that contain the instructions for the development and functioning of all life forms, including the development of physical traits and body parts that correspond with each biological sex.
Humans who inherit two X chromosomes typically develop as females, while humans with one X and one Y chromosome typically develop as males. Sex determination is the beginning of the development of many characteristics that influence how a human looks and functions as well as the societal expectations that other humans have for each other. The process of sex determination begins after fertilization, a process where male and female germ cells fuse to form a zygote, or a single-celled, fertilized egg.
Germ cells are those that carry genetic information from parents to offspring during fertilization. Male germ cells are sperm cells and female germ cells are egg cells. When the egg and sperm cells fuse, the zygote divides into multiple cells and later forms an embryo. The combination of sex chromosomes that an embryo inherits from germ cells determines what biological sex it will later develop as. Meiosis occurs inside of the testes and ovaries, the organs in males and females, respectively, that produce germ cells.
During meiosis, each cell divides twice, which results in four cells. When the germ cells fuse during fertilization, the resulting embryo will have the normal amount of genetic material, including two sex chromosomes, because it receives one from each parent. Because females tend to only have X chromosomes, the egg cells that they produce typically carry an X chromosome, while the male sperm cell can carry either an X or Y.